Team
Scientists Dr. Mateusz Chwastyk, assistant professor Dr. Izabela Kamińska, assistant professor Dr. Dinh Quoc Huy Pham, assistant professor Dr. Radost Waszkiewicz, assistant professor | Engineering and technical staff MSc. Eng. Agnieszka Michaś MSc. Zuzanna Staszałek
PhD Students MSc. Michał Białobrzewski MSc. Barbara Klepka |
The Laboratory of Biological Physics (SL 4) is engaged in research in the domain of molecular biophysics and nanotechnology of biologically functionalised quantum dots. The objective of this research is to elucidate the physical basis of biological phenomena at the molecular level and to create biologically functionalised nanoparticles for potential applications in cancer theranostics.
The primary focus of our research in molecular biophysics is the structural dynamics and interactions of proteins, with a particular emphasis on intrinsically disordered proteins (IDPs). These proteins play a crucial role in regulating key cellular processes; on the other hand, their malfunction is associated with various pathologies, including neurodegenerative diseases. Our experimental research primarily aims to undersand the conformational dynamics and its influence on molecular mechanisms of interactions between IDPs that are involved in the regulation of gene expression in eukaryotic organisms and viruses, as well as in biomineralisation. Our research focuses on the hydrodynamic properties of IDPs, the interactions that occur between them, and liquid-liquid phase transitions that lead to the formation of protein droplets. In the context of biomineralisation, we also investigate the nucleation and crystal growth processes that are controlled by proteins. Our experimental approach combines spectroscopic, microscopic, hydrodynamic and thermodynamic methods. The field of biophysical theoretical work focuses on the process of protein folding and misfolding, their conformational changes, aggregation, the behaviour of biomolecules at phase boundaries, and the formation of protein droplets as a result of liquid-liquid phase separation. The research is based on molecular dynamics simulations, employing both full-atom and coarse-grained models.
Our research on multifunctional magnetic and opto-magnetic bionanomaterials is based on up-converting nanoparticles (UCNPs), which can convert infrared light ‘upward’ into visible light. The studies are conducted as part of the statutory topic: “Synthesis of passivated biosensor nanostructures”. Developing efficient techniques for the colloidal synthesis of UCNPs and their biofunctionalisation, along with toxicity testing, could potentially lead to the design of biomedical applications. Our goal is thus to produce, characterise and evaluate the interaction between UCNPs and cells and tissues for potential use in imaging, targeted cancer diagnostics, phototherapy and magnetic hyperthermia.
Projects
- Elemental signatures in fossil and modern otoliths: Proxies for biomineralizing protein functionality and diagenetic alteration
NCN 2024/55/B/ST10/02006, 2025-2029 (consortium with Institute of Paleobiology, Polish Academy of Sciences and Wrocław University of Technology)
Principal Investigator at IP PAS: Dr. hab. Anna Niedźwiecka, prof. IP PAS - Liquid-liquid phase separation of GW182 silencing domain - biophysical bases of biomolecular condensates formation relevant to microRNA-mediated gene silencing
NCN 2023/49/N/NZ1/04320, 2024-2026
Principal Investigator: MSc. Michał Białobrzewski - Upconverting/magnetic core/shell nanoparticles (magnetite/Gd2O3: Yb, Er, Mg, Nd) as markers in biology and medicine
Miniatura NCN 2022/06/X/ST5/00026
Principal Investigator: Dr. Izabela Kamińska - Optical-numerical recognition of nanoparticle suspensions in evaporating microdroplets
NCN 2021/41/B/ST3/00069
Co-investigator: Dr. Izabela Kamińska - Thermal History Coatings for Research and Development of Space Technologies
The National Centre for Research and Development, POIR.01.01.01-00-0832/19, 2020-2023 (consortium with the Łukasiewicz Research Network, the Institute of Aviation and the Institute of Microelectronics and Photonics)
Task Leader at IP PAS : Dr. Izabela Kamińska - Multiscale and multiphase molecular dynamics of disordered proteins and proteinceous liquid droplets
NCN 2018/31/B/NZ1/00047
Principal Investigator: Prof. Dr. hab. Marek Cieplak (2019-2021), Dr. Mateusz Chwastyk (2022-2024) - Studies of interactions and dynamics of intrinsically disordered proteins in crucial biological processes - biophysical perspective including single molecule approachSonata-Bis NCN 2016/22/E/NZ1/00656, 2017-2024
Principal Investigator: Dr. hab. Anna Niedźwiecka, prof. IP PAS - New Blue Revolution through a pioneering pathogen-trapping technology based on bioselective hydrogel-forming proteins
Horyzont 2020 899616 (PathoGelTrap)
Polish Team Leader: Prof. Dr. hab. Marek Cieplak (2020-2021), Dr. Mateusz Chwastyk (2022-2023)
Project Coordinator: Dr. Mateusz Chwastyk (2024)
Selected publications
- Dynamics of biomolecules
- Klepka BP, Waszkiewicz R, Wojciechowski M, Michaś A, Niedzwiecka A
Electrostatic Collapse of Intrinsically Disordered Acid-Rich Protein Is Sensitive to Counterion Valency
J Phys Chem Lett 2025, doi: 10.1021/acs.jpclett.5c02098 - Klepka BP, Michaś A, Wojciechowski T, Niedzwiecka A
Biomineralization Controlled by Liquid-Liquid Phase Separation of a Highly Charged Protein.
Small 2025, doi: 10.1002/smll.202506227 - Cieplak-Rotowska MK, Dadlez M, Niedzwiecka A
Exploring the CNOT1(800-999) HEAT Domain and Its Interactions with Tristetraprolin (TTP) as Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry
Biomolecules 2025, doi: 10.3390/biom15030403 - Sozańska N, Klepka BP, Niedzwiecka A, Zhukova L, Dadlez M, Greb-Markiewicz B, Ożyhar A, Tarczewska A
The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor
Cell Commun Signal 2025, doi: 10.1186/s12964-025-02154-7 - Waszkiewicz R, Lisicki M
The trimer paradox: The effect of stiff constraints on equilibrium distributions in overdamped dynamics
J Chem Phys 2025, doi: 10.1063/5.0265585 - Duong LV, Pham-Tran PA, Chwastyk M, Pham-Ho MP, Nguyen MT
A ternary Li3B7Si3 cluster: when reduced electron delocalization enhances thermodynamic stability
RSC Adv 2025, doi: 10.1039/d5ra04954g - Anila MM, Wojciechowski M, Chwastyk M, Różycki B
Theoretical Methods for Assessing the Density of Protein Nanodroplets
Int J Mol Sci 2025, doi: 10.3390/ijms26178631 - Truong DT, Chwastyk M, Phung VBT, Nguyen MT
Presence of EGF ligand restricts the binding ability of EgB4 nanobody to EGFR extracellular domain
Sci Rep 2025, doi: 10.1038/s41598-025-86646-z - Pham DQH, Anila MM, Chwastyk M
Clustering-base Method for Constructing the Phase Diagram of the Van Der Waals Model Fluid
Curr Protein Pept Sci 2025, doi: 10.2174/0113892037360348250528003832 - Waszkiewicz R, Michaś A, Białobrzewski MK, Klepka BP, Cieplak-Rotowska MK, Staszałek Z, Cichocki B, Lisicki M, Szymczak P, Niedzwiecka A
Hydrodynamic Radii of Intrinsically Disordered Proteins: Fast Prediction by Minimum Dissipation Approximation and Experimental Validation
J Phys Chem Lett 2024, doi: 10.1021/acs.jpclett.4c00312 - Truong DT, Ho K, Pham DQH, Chwastyk M, Nguyen-Minh T, Nguyen MT
Treatment of flexibility of protein backbone in simulations of protein-ligand interactions using steered molecular dynamics
Sci Rep 2024, doi:10.1038/s41598-024-59899-3 - Varenyk Y, Theodorakis PE, Pham DQH, Li MS, Krupa P
Exploring Structural Insights of Aβ42 and α-Synuclein Monomers and Heterodimer: A Comparative Study Using Implicit and Explicit Solvent Simulations
J Phys Chem B 2024, doi: 10.1021/acs.jpcb.4c00503 - Cofas-Vargas LF, Olivos-Ramirez GE, Chwastyk M, Moreira RA, Baker JL, Marrink SJ, Poma AB
Nanomechanical footprint of SARS-CoV-2 variants in complex with a potent nanobody by molecular simulations
Nanoscale 2024, doi: 10.1039/d4nr02074j. PMID: 39351797 - Białobrzewski MK, Klepka BP, Michaś A, Cieplak-Rotowska MK, Staszałek Z, Niedźwiecka A
Diversity of hydrodynamic radii of intrinsically disordered proteins
Eur Biophys J 2023, doi: 10.1007/s00249-023-01683-8 - Pham DQH, Chwastyk M, Cieplak M
The coexistence region in the Van der Waals fluid and the liquid-liquid phase transitions
Front Chem 2023, doi: 10.3389/fchem.2022.1106599 - Loch JI, Worsztynowicz P, Sliwiak J, Grzechowiak M, Imiolczyk B, Pokrywka K, Chwastyk M, Gilski M, Jaskolski M
Rhizobium etli has two L-asparaginases with low sequence identity but similar structure and catalytic center
Acta Crystallogr D Struct Biol 2023, doi: 10.1107/S2059798323005648 - Cieplak M, Mioduszewski Ł, Chwastyk M
Contact-Based Analysis of Aggregation of Intrinsically Disordered Proteins
Methods Mol Biol 2022, doi: 10.1007/978-1-0716-1546-1_6 - Mykuliak VV, Sikora M, Booth JJ, Cieplak M, Shalashilin DV, Hytönen VP
Mechanical Unfolding of Proteins-A Comparative Nonequilibrium Molecular Dynamics
Study Biophys J 2020, doi: 10.1016/j.bpj.2020.07.030 - Cieplak M, Chwastyk M, Mioduszewski Ł, de Aquino BRH
Transient knots in intrinsically disordered proteins and neurodegeneration
Prog Mol Biol Transl Sci 2020, doi: 10.1016/bs.pmbts.2020.03.003 - Mioduszewski Ł , Cieplak M
Protein droplets in systems of disordered homopeptides and the amyloid glass phase
Phys Chem Chem Phys 2020, doi: 10.1039/d0cp01635g - Mioduszewski Ł, Różycki B, Cieplak M
Pseudo-Improper-Dihedral Model for Intrinsically Disordered Proteins
J Chem Theory Comput 2020, doi: 10.1021/acs.jctc.0c00338 - Chwastyk M, Cieplak M
Conformational Biases of α-Synuclein and Formation of Transient Knots
J Phys Chem B 2020, doi: 10.1021/acs.jpcb.9b08481 - Demarchi CA, da Silva LM, Niedźwiecka A, Ślawska-Waniewska A, Lewińska S, Dal Magro J, Fossá Calisto JF, Martello R, Rodrigues CA
Nanoecotoxicology study of the response of magnetic O-Carboxymethylchitosan loaded silver nanoparticles on Artemia salina
Environ Toxicol Pharmacol 2020, doi: 10.1016/j.etap.2019.103298 - Cieplak-Rotowska MK, Tarnowski K, Rubin M, Fabian MR, Sonenberg N, Dadlez M, Niedzwiecka A
Structural Dynamics of the GW182 Silencing Domain Including its RNA Recognition motif (RRM) Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry
J Am Soc Mass Spectrom 2018, doi: 10.1007/s13361-017-1830-9 - Mioduszewski Ł , Cieplak M
Disordered peptide chains in an α-C-based coarse-grained model
Phys Chem Chem Phys 2018, doi: 10.1039/c8cp03309a - Pham DQH, Li MS, La Penna G
Copper Binding Induces Polymorphism in Amyloid-β Peptide: Results of Computational Models
J Phys Chem B 2018, doi: 10.1021/acs.jpcb.8b03983 - Kocmik I, Piecyk K, Rudzinska M, Niedzwiecka A, Darzynkiewicz E, Grzela R, Jankowska-Anyszka M
Modified ARCA analogs providing enhanced translational properties of capped mRNAs
Cell Cycle 2018, doi: 10.1080/15384101.2018.1486164 - Niedzwiecka A, Nilsson P, Worch R, Stepinski J, Darzynkiewicz E, Virtanen A
Molecular recognition of mRNA 5' cap by 3' poly(A)-specific ribonuclease (PARN) differs from interactions known for other cap-binding proteins
Biochim Biophys Acta 2016, doi: 10.1016/j.bbapap.2016.01.002 - Różycki B, Cieplak M
Stiffness of the C-terminal disordered linker affects the geometry of the active site in endoglucanase Cel8A
Mol Biosyst 2016, doi: 10.1039/c6mb00606j - Różycki B, Cieplak M, Czjzek M
Large conformational fluctuations of the multi-domain xylanase Z of Clostridium thermocellum
J Struct Biol 2015, doi: 10.1016/j.jsb.2015.05.004 - Gómez-Sicilia À, Sikora M, Cieplak M, Carrión-Vázquez M
An Exploration of the Universe of Polyglutamine Structures
PLoS Comput Biol 2015, doi: 10.1371/journal.pcbi.1004541 - Piecyk K, Niedzwiecka A, Ferenc-Mrozek A, Lukaszewicz M, Darzynkiewicz E, Jankowska-Anyszka M
How to find the optimal partner - studies of snurportin 1 interactions with U snRNA 5' TMG-cap analogues containing modified 2-amino group of 7-methylguanosine
Bioorg Med Chem 2015, doi: 10.1016/j.bmc.2015.05.054 - Zytek M, Kowalska J, Lukaszewicz M, Wojtczak BA, Zuberek J, Ferenc-Mrozek A, Darzynkiewicz E, Niedzwiecka A, Jemielity J
Towards novel efficient and stable nuclear import signals: synthesis and properties of trimethylguanosine cap analogs modified within the 5',5'-triphosphate bridge
Org Biomol Chem 2014, doi: 10.1039/c4ob01579g. - Chwastyk M, Galera-Prat A, Sikora M, Gómez-Sicilia À, Carrión-Vázquez M, Cieplak M
Theoretical tests of the mechanical protection strategy in protein nanomechanics
Proteins 2014, doi: 10.1002/prot.24436 - Modrak-Wojcik A, Gorka M, Niedzwiecka K, Zdanowski K, Zuberek J, Niedzwiecka A, Stolarski R
Eukaryotic translation initiation is controlled by cooperativity effects within ternary complexes of 4E-BP1, eIF4E, and the mRNA 5' cap
FEBS Lett 2013, doi: 10.1016/j.febslet.2013.10.043 - Thompson D, Sikora M, Szymczak P, Cieplak M
A multi-scale molecular dynamics study of the assembly of micron-size supraparticles from 30 nm alkyl-coated nanoparticles
Phys Chem Chem Phys 2013, doi: 10.1039/c3cp50523e - Sikora M, Cieplak M
Formation of cystine slipknots in dimeric proteins
PLoS One 2013, doi: 10.1371/journal.pone.0057443 - Cieplak M, Sikora M
Topological features in stretching of proteins
Biochem Soc Trans 2013, doi: 10.1042/BST20120289 - Sikora M, Cieplak M
Cystine plug and other novel mechanisms of large mechanical stability in dimeric proteins
Phys Rev Lett 2012, doi: 10.1103/PhysRevLett.109.208101 - Sikora M, Adam D, Korczyk PM, Prodi-Schwab A, Szymczak P, Cieplak M
Geometrical and electrical properties of indium tin oxide clusters in ink dispersions
Langmuir 2012, doi: 10.1021/la203886b - Liu W, Jankowska-Anyszka M, Piecyk K, Dickson L, Wallace A, Niedzwiecka A, Stepinski J, Stolarski R, Darzynkiewicz E, Kieft J, Zhao R, Jones DN, Davis RE
Structural basis for nematode eIF4E binding an m(2,2,7)G-Cap and its implications for translation initiation
Nucleic Acids Res 2011, doi: 10.1093/nar/gkr650 - Niedzwiecka A, Lekka M, Nilsson P, Virtanen A
Global architecture of human poly(A)-specific ribonuclease by atomic force microscopy in liquid and dynamic light scattering
Biophys Chem 2011, doi: 10.1016/j.bpc.2011.06.010 - Kiraga-Motoszko K, Niedzwiecka A, Modrak-Wojcik A, Stepinski J, Darzynkiewicz E, Stolarski R
Thermodynamics of molecular recognition of mRNA 5' cap by yeast eukaryotic initiation factor 4E
J Phys Chem B 2011, doi: 10.1021/jp2012039 - Sikora M, Szymczak P, Thompson D, Cieplak M
Linker-mediated assembly of gold nanoparticles into multimeric motifs
Nanotechnology 2011, doi: 10.1088/0957-4484/22/44/445601 - Sikora M, Cieplak M
Mechanical stability of multidomain proteins and novel mechanical clamps
Proteins 2011, doi: 10.1002/prot.23001 - Wu M, Nilsson P, Henriksson N, Niedzwiecka A, Lim MK, Cheng Z, Kokkoris K, Virtanen A, Song H
Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease
Structure 2009, doi: 10.1016/j.str.2008.11.012 - Worch R, Jankowska-Anyszka M, Niedzwiecka A, Stepinski J, Mazza C, Darzynkiewicz E, Cusack S, Stolarski R
Diverse role of three tyrosines in binding of the RNA 5' cap to the human nuclear cap binding complex
J Mol Biol 2009, doi: 10.1016/j.jmb.2008.10.092 - Liu W, Zhao R, McFarland C, Kieft J, Niedzwiecka A, Jankowska-Anyszka M, Stepinski J, Darzynkiewicz E, Jones DN, Davis RE
Structural insights into parasite eIF4E binding specificity for m7G and m2,2,7G mRNA caps
J Biol Chem 2009, doi: 10.1074/jbc.M109.049858 - Sułkowska JI, Sulkowski P, Szymczak P, Cieplak M
Stabilizing effect of knots on proteins
Proc Natl Acad Sci USA 2008, doi: 10.1073/pnas.0805468105 - Rutkowska-Wlodarczyk I, Stepinski J, Dadlez M, Darzynkiewicz E, Stolarski R, Niedzwiecka A
Structural changes of eIF4E upon binding to the mRNA 5' monomethylguanosine and trimethylguanosine Cap
Biochemistry 2008, doi: 10.1021/bi701168z - Nilsson P, Henriksson N, Niedzwiecka A, Balatsos NA, Kokkoris K, Eriksson J, Virtanen A
A multifunctional RNA recognition motif in poly(A)-specific ribonuclease with cap and poly(A) binding properties
J Biol Chem 2007, doi: 10.1074/jbc.M702375200 - Niedzwiecka A, Stepinski J, Antosiewicz JM, Darzynkiewicz E, Stolarski R
Biophysical approach to studies of cap-eIF4E interaction by synthetic cap analogs
Methods Enzymol 2007, doi: 10.1016/S0076-6879(07)30009-8 - Worch R, Niedzwiecka A, Stepinski J, Mazza C, Jankowska-Anyszka M, Darzynkiewicz E, Cusack S, Stolarski R
Specificity of recognition of mRNA 5' cap by human nuclear cap-binding complex
RNA 2005, doi: 10.1261/rna.2850705 - Niedzwiecka A, Darzynkiewicz E, Stolarski R
Thermodynamics of mRNA 5' cap binding by eukaryotic translation initiation factor eIF4E
Biochemistry 2004, doi: 10.1021/bi0491651
- Klepka BP, Waszkiewicz R, Wojciechowski M, Michaś A, Niedzwiecka A
- Synthesis of passivated biosensor nanostructures
Shopa Y, Kolwas M, Jakubczyk D, Derkachov G, Kamińska I, Fronc K, Wojciechowski T
Up-Converting Luminescent Nanoparticles as Probes of Surface Dynamics in Single Evaporating Microdroplets of Suspension
J Phys Chem C 2025, doi: https://doi.org/10.1021/acs.jpcc.5c00174Stryczniewicz W, Chmielewski C, Sobczak K, Szajna E, Fronc K, Chojnacki M, Kamińska I
Off-Line temperature profiling of Mo-based rocket engine combustion chamber using thermal history paint
Applied Thermal Engineering 2025, doi: https://doi.org/10.1016/j.applthermaleng.2025.127661Kamińska I, Wojciechowski T, Minikayev R, Chojnacki M, Sobczak K, Stryczniewicz W, Fronc K
Influence of high energy ball milling on structural and optical properties of Gd2O3: 1% Er3+, 18% Yb3+ nanoparticles supplemented with NaCl
Ceramics International 2025, doi: https://doi.org/10.1016/j.ceramint.2025.03.272- Zajdel K, Lobaz V, Ondra M, Konefał R, Moravec O, Pop-Georgievski O, Pánek J, Kalita D, Sikora-Dobrowolska B, Lenart L, Hajdúch M, Hrubý M, Pruszyński M
May the target be with you: polysaccharide-coated upconverting nanoparticles for macrophage targeting
Nanoscale 2025, doi: 10.1039/d5nr01833a - Duda M, Joshi P, Borodziuk A, Sobczak K, Sikora-Dobrowolska B, Maćkowski S, Dennis AM, Kłopotowski Ł
Multimodal Temperature Readout Boosts the Performance of CuInS<sub>2</sub>/ZnS Quantum Dot Nanothermometers
ACS Appl Mater Interfaces 2024, doi: 10.1021/acsami.4c14541 - Stryczniewicz W, Fronc K, Chojnacki M, Sobczak K, Szajna E, Leśniewska-Matys K, Kozłowska A, Kamińska I
Upconverting thermal history paint for investigations of short thermal events
Sensors and Actuators A: Physical 2024, doi: https://doi.org/10.1016/j.sna.2024.115980 Kamińska I, Sobczak K, Zhydachevskyy Y, Wojciechowski T, Minikayev R, Sikora-Dobrowolska B, Lewińska S, Chojnacki M, Fronc K
Hybrid upconverting/paramagnetic Fe3O4/Gd2O3:Er3+, Yb3+, Mg2+, Nd3+ nanoparticles – synthesis, characterization and biological applications
Opto-Electronics Review 2024, doi: https://doi.org/10.24425/opelre.2024.150182- Zajdel K, Bartczak D, Frontczak-Baniewicz M, Ramsay DA, Kowalik P, Sobczak K, Kamińska I, Wojciechowski T, Minikayev R, Goenaga-Infante H, Sikora B
Nano-bio interactions of upconversion nanoparticles at subcellular level: biodistribution and cytotoxicity
Nanomedicine (Lond) 2023, doi: 10.2217/nnm-2022-0320 - Zajdel K, Janowska J, Frontczak-Baniewicz M, Sypecka J, Sikora B
Upconverting Nanoparticles as a New Bio-Imaging Strategy-Investigating Intracellular Trafficking of Endogenous Processes in Neural Tissue
Int J Mol Sci 2023, doi: 10.3390/ijms24021122 - Shopa I, Kolwas M, Kamińska I, Derkachov G, Nyandey K, Jakubczyk T, Wojciechowski T, Derkachova A, Jakubczyk D
Luminescent nanoparticles in a shrinking spherical cavity - probing the evaporating microdroplets of colloidal suspension - optical lattices and structural transitions
J Quant Spectrosc Radiat Transfer 2023, doi: https://doi.org/10.1016/j.jqsrt.2022.108439 - Jodko-Piórecka K, Sikora B, Kluzek M, Przybylski P, Litwinienko G
Antiradical Activity of Dopamine, L-DOPA, Adrenaline, and Noradrenaline in Water/Methanol and in Liposomal Systems
J Org Chem 2022, doi: 10.1021/acs.joc.1c02308 - Kamińska I, Wosztyl A, Kowalik P, Sikora B, Wojciechowski T, Sobczak K, Minikayev R, Zajdel K, Chojnacki M, Zaleszczyk W, Łysiak K, Paszkowicz W, Szczytko J, Frontczak-Baniewicz M, Stryczniewicz W, Fronc K
Synthesis and characterization of Gd2O3: Er3, Yb3+ doped with Mg+, Li+ ions-effect on the photoluminescence and biological applications
Nanotechnology 2021, doi: 10.1088/1361-6528/abed02 - Kowalik P, Kamińska I, Fronc K, Borodziuk A, Duda M, Wojciechowski T, Sobczak K, Kalinowska D, Klepka MT, Sikora B
The ROS-generating photosensitizer-free NaYF4:Yb,Tm@SiO2 upconverting nanoparticles for photodynamic therapy application
Nanotechnology 2021, doi: 10.1088/1361-6528/abe892 - Kowalik P, Mikulski J, Borodziuk A, Duda M, Kamińska I, Zajdel K, Rybusinski J, Szczytko J, Wojciechowski T, Sobczak K, Minikayev R, Kulpa-Greszta M, Pazik R, Grzaczkowska P, Fronc K, Lapinski M, Frontczak- Baniewicz M, Sikora B
Yttrium-Doped Iron Oxide Nanoparticles for Magnetic Hyperthermia Applications
J Phys Chem C Nanomater Interfaces 2020, doi: 10.1021/acs.jpcc.9b11043 - Kamińska I, Jankowski D, Sikora B, Kowalik P, Minikayev R, Wojciechowski T, Chojnacki M, Sobczak K, Rybusiński J, Szczytko J, Zajdel K, Suchocki A, Paszkowicz W, Frontczak-Baniewicz M, Fronc K
Structural, optical and magnetic properties of Y3-0.02-xEr0.02YbxAl5O12 nanocrystals: effect of Yb content
Nanotechnology 2020, doi: 10.1088/1361-6528/ab73b9 - Borodziuk A, Baranowski M, Wojciechowski T, Minikayev R, Sikora B, Maude DK, Plochocka P, Kłopotowski Ł
Excitation efficiency determines the upconversion luminescence intensity of β-NaYF4:Er3+,Yb3+ nanoparticles in magnetic fields up to 70 T
Nanoscale 2020, doi: 10.1039/d0nr04252h - Borodziuk A, Kowalik P, Duda M, Wojciechowski T, Minikayev R, Kalinowska D, Klepka M, Sobczak K, Kłopotowski Ł, Sikora B
Unmodified Rose Bengal photosensitizer conjugated with NaYF4:Yb,Er upconverting nanoparticles for efficient photodynamic therapy
Nanotechnology 2020, doi: 10.1088/1361-6528/aba975. PMID: 32717731 - Kamińska I, Elbaum D, Sikora B, Kowalik P, Mikulski J, Felcyn Z, Samol P, Wojciechowski T, Minikayev R, Paszkowicz W, Zaleszczyk W, Szewczyk M, Konopka A, Gruzeł G, Pawlyta M, Donten M, Ciszak K, Zajdel K, Frontczak-Baniewicz M, Stępień P, Łapiński M, Wilczyński G, Fronc K
Single-step synthesis of Er3+ and Yb3+ ions doped molybdate/Gd2O3 core-shell nanoparticles for biomedical imaging
Nanotechnology 2018, doi: 10.1088/1361-6528/aa9974 - Sikora B, Kowalik P, Mikulski J, Fronc K, Kamińska I, Szewczyk M, Konopka A, Zajdel K, Minikayev R, Sobczak K, Zaleszczyk W, Borodziuk A, Rybusiński J, Szczytko J, Sienkiewicz A, Wojciechowski T, Stępień P, Frontczak-Baniewicz M, Łapiński M, Wilczyński G, Paszkowicz W, Twardowski A, Elbaum D
Mammalian cell defence mechanisms against the cytotoxicity of NaYF4:(Er,Yb,Gd) nanoparticles
Nanoscale 2017, doi: 10.1039/c7nr03705h - Iskierko Z, Sosnowska M, Sharma PS, Benincori T, D'Souza F, Kaminska I, Fronc K, Noworyta K
Extended-gate field-effect transistor (EG-FET) with molecularly imprinted polymer (MIP) film for selective inosine determination
Biosens Bioelectron 2015, doi: 10.1016/j.bios.2015.06.073 - Sikora B, Fronc K, Kamińska I, Koper K, Szewczyk S, Paterczyk B, Wojciechowski T, Sobczak K, Minikayev R, Paszkowicz W, Stępień P, Elbaum D
Transport of NaYF4:Er3+, Yb3+ up-converting nanoparticles into HeLa cells
Nanotechnology 2013, doi: 10.1088/0957-4484/24/23/235702 - Kamińska I, Sikora B, Fronc K, Dziawa P, Sobczak K, Minikayev R, Paszkowicz W, Elbaum D
Novel ZnO/MgO/Fe2O3 composite optomagnetic nanoparticles
J Phys Condens Matter 2013, doi: 10.1088/0953-8984/25/19/194105 - Sikora B, Fronc K, Kamińska I, Koper K, Stępień P, Elbaum D
Luminescence of colloidal ZnO nanoparticles synthesized in alcohols and biological application of ZnO passivated by MgO
J Phys Condens Matter 2013, doi: 10.1088/0953-8984/25/19/194104
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